NPE

NPE may refer to:

Transport

 * Napier Airport, New Zealand, by IATA code
 * New Pantai Expressway, an expressway in Klang Valley region, Malaysia
 * Nationale Plattform Elektromobilität, the German National Platform for Electric Mobility

Science and technology

 * New political economy, a sub-school within the field of political economy
 * Nonylphenol ethoxylates, mixtures of nonionic surfactants
 * Non-paternity event, a paternal relationship that is shown to be false through DNA testing
 * Norton Power Eraser, a tool that scans a computer system for threats
 * Null pointer exception, a form of run-time error in many programming languages

Other

 * National Party of Europe, in politics
 * National Policy on Education, in India
 * New Popular Edition, maps published by the Ordnance Survey
 * Non-practicing entity, a type of patent owner