NPMD

NPMD may refer to:
 * Non-psychotic major depressive disorder, in order to distinguish this condition from psychotic major depression (PMD)
 * North Papuan Mainland–D'Entrecasteaux languages, a putative group of Papuan Tip languages
 * Network Performance Monitoring & Diagnostics
 * Nerdy Prudes Must Die, a 2023 musical by StarKid Productions