NPSA

NPSA may refer to:
 * National Park of American Samoa
 * National Pedal Sport Association, south-eastern US regional BMX sanctioning body 1974–1988
 * National Patient Safety Agency, part of the National Health Service of the United Kingdom
 * National Public Schools Association, group taking part in the National education campaign in the United Kingdom (1837–1870)
 * National Party South Africa
 * National Protective Security Authority
 * Northeastern Political Science Association