NSMB

NSMB may refer to:


 * NSMB (mathematics), a Navier-Stokes finite volume solver
 * Nature Structural & Molecular Biology, an academic journal
 * New Super Mario Bros. (series), a series of 2D platform games by Nintendo consisting of new revivals of classic Mario platformers
 * New Super Mario Bros., the first game in the series, released in 2006 for the Nintendo DS
 * , Server Message Block implementation on FreeBSD and other BSD systems including macOS