O'Reilly, Mississippi

O'Reilly is an unincorporated community located in Bolivar County, Mississippi, United States, along U.S. Route 61. O'Reilly is approximately 3 mi south of Boyle and approximately 6 mi north of Shaw. O'Reilly is located on the former Yazoo and Mississippi Valley Railroad.

A post office operated under the name O'Reilly from 1903 to 1926.