O. spinosa

O. spinosa may refer to:
 * Ochrotrichia spinosa, a microcaddisfly species in the genus Ochrotrichia
 * Octonoba spinosa, a non-venomous spider species in the genus Octonoba
 * Oncoba spinosa, a flowering plant species
 * Onigocia spinosa, a fish species in the genus Onigocia
 * Ononis spinosa, a medicinal plant species
 * Ophellantha spinosa, a plant species in the genus Ophellantha
 * Opopaea spinosa, a spider species in the genus Opopaea and the family Oonopidae
 * Ovalia spinosa, a harvestman species in the genus Ovalia