OBF

OBF may refer to:
 * OBF (band), 2012 rename of The Original Bucks Fizz
 * Open Bioinformatics Foundation, non-profit organization supporting open source programming in bioinformatics.
 * Oregon Bach Festival, an annual midsummer J. S. Bach festival in Eugene, Oregon
 * Oregon Brewers Festival, an annual craft beer festival
 * Out of Box Failure, computer hardware term
 * Ordovician Bellefonte Formation, a rock formation in central Pennsylvania
 * Oberpfaffenhofen Airport's IATA code
 * Orthonormal Basis Function as in Hilbert space