Ohio State Route 160

State Route 160 (SR 160) is a north–south state highway in the southeastern portion of the U.S. state of Ohio. Its southern terminus is at SR 7 in Gallipolis, and the route heads north. It meets U.S. Route 35 at an interchange with various collector and distributor ramps. SR 160 southbound bypasses the interchange on a 0.739 mi road officially designated SR 160-A. From there, the route passes through Vinton in northern Gallia County. Following an intersection with SR 32, the route heads in a more westerly direction until it meets and its northern terminus is at State Route 93 in Hamden.

1926
Original route certified; routed from 3 mi north of Gallipolis to Hamden along the previous alignment of State Route 142 from 3 mi north of Gallipolis to 4 mi north of Radcliff, and along a previously unnumbered road from 4 mi north of Radcliff to Hamden.

1970
Extended south to Gallipolis along the previous alignment of U.S. Route 35 (which was the former State Route 11 before 1926).