Opie

Opie may refer to:


 * Opie (name), a list of people and fictional characters with the given name, nickname, or surname
 * Acronyms OPIE:
 * OPIE (Entomology) (Office pour l'Information Eco-entomologique), a French government organisation devoted to entomology
 * OPIE Authentication System, a one-time password authentication system for Unix based on S/KEY