Osypenko (surname)

Osypenko or Osipenko (Осипенко) is a Ukrainian surname derived from the given name Osyp, equivalent to English Joseph. Its Belarusian equivalent is Asipenka or Asipienka (Асіпенка).

Notable people with the surname include:
 * Alexander Osipenko (disambiguation), multiple individuals
 * Alla Osipenko (born 1932), Russian ballerina
 * Dzmitry Asipenka (born 1982), Belarusian footballer
 * Inna Osypenko-Radomska (born 1982), Ukrainian-Azerbaijani sprint kayaker
 * Petro Osypenko (1921–unknown), Soviet-Ukrainian public prosecutor
 * Polina Osipenko (1907–1939), Soviet-Ukrainian pilot