Oxbow orthohantavirus

Oxbow virus (OXBV) is a single-stranded, enveloped, negative-sense RNA orthohantavirus.

Natural reservoir
Oxbow virus was isolated from an American shrew mole (Neurotrichus gibbsii), captured in Gresham, Oregon, in September 2003.

Virology
The genome of the Oxbow virus along the full length of the S, M, and partial L-segment nucleotide and amino acid sequences show a low sequence similarity to rodent-borne hantaviruses. Phylogenetic analysis demonstrated that Oxbow virus and Asama virus are related to soricine shrew-borne hantaviruses found in North America, Europe, and Asia. This suggests both these viruses evolved with cross-species transmission.