PC1

PC1 may refer to:
 * Furin, an enzyme
 * Proprotein convertase 1, an enzyme
 * Polycystin 1, a protein in humans associated with autosomal dominant polycystic kidney disease
 * PC-1, a submarine telecommunications cable system (Pacific Crossing 1)
 * PC1 cipher, used by the Amazon Kindle and some boot loaders
 * First principal component in principal component analysis, often used in genetic distance visualizations