PLAG1

Zinc finger protein PLAG1 is a protein that in humans is encoded by the PLAG1 gene.

Function
Pleomorphic adenoma gene 1 encodes a zinc finger protein with 2 putative nuclear localization signals. PLAG1, which is developmentally regulated, has been shown to be consistently rearranged in pleomorphic adenomas of the salivary glands. PLAG1 is activated by the reciprocal chromosomal translocations involving 8q12 in a subset of salivary gland pleomorphic adenomas.

Interactions
PLAG1 has been shown to interact with Karyopherin alpha 2.