PLK

PLK may refer to:


 * PLK (rapper) (born 1997), French rapper of Polish and Corsican origin
 * PKP PLK, a Polish railroad company
 * PLK Vicwood KT Chong Sixth Form College
 * Polska Liga Koszykówki, Polish Basketball League
 * Pulkovo Airlines, ICAO airline designator
 * M. Graham Clark Downtown Airport, Missouri, USA, IATA code
 * Po Leung Kuk, a Hong Kong charitable organisation
 * Polo-like kinase, regulators of the cell cycle (mitosis)