PSSM

PSSM may refer to:
 * Parallel-Split Shadow Map
 * Position-Specific Scoring Matrix
 * Pretty Soldier Sailor Moon, the official English translation of the series, often shortened as Sailor Moon
 * Principles and Standards for School Mathematics, a policy book on mathematics education
 * Polysaccharide storage myopathy, aka Equine polysaccharide storage myopathy (PSSM or EPSM), a disease in horses
 * Positive sleep state misperception, subjective hypersomnia without objective findings.
 * Rhizobium leguminosarum exopolysaccharide glucosyl ketal-pyruvate-transferase, an enzyme