Palestine High School

Palestine High School could mean:


 * Palestine High School (Illinois), a public school in Palestine, Illinois and Palestine Community Unit School District 3; teams are the Pioneers or Tigers
 * Palestine High School (Ohio), a defunct public school in Palestine, Ohio
 * Palestine High School (Texas), the current public high school in Palestine, Texas and the Palestine Independent School District; teams are the Wildcats
 * Palestine–Wheatley High School, a public school in Palestine, Arkansas and the Palestine–Wheatley School District; teams are the Patriots
 * Museum for East Texas Culture, whose historic building was formerly known as Palestine High School