Panther Creek (East Fork Grand River tributary)

Panther Creek is a stream in Gentry and Harrison counties of northern Missouri. It is a tributary of the East Fork Grand River.

The stream headwaters in Harrison County are located at 40.3925°N, -94.1525°W and the confluence with the East Fork is at 40.30167°N, -94.34778°W.

According to tradition, Panther Creek was so named on account of some pioneers encountering panthers along its course.