Panther Creek (James River tributary)

Panther Creek is a stream in the Webster County, Missouri. It is a tributary of the James River.

The stream source is at 37.1625°N, -92.89°W and the confluence with the James River is at 37.21889°N, -93.05194°W. The headwaters are adjacent to U. S. Route 60 between Fordland and Diggins.

Panther Creek was so named due to reports of panthers in the area.