ParaHoxozoa

ParaHoxozoa (or Parahoxozoa) is a clade of animals that consists of Bilateria, Placozoa, and Cnidaria. The relationship of this clade relative to the two other animal lineages Ctenophora and Porifera is debated. Some phylogenomic studies have presented evidence supporting Ctenophora as the sister to Parahoxozoa and Porifera as the sister group to the rest of animals (e.g.  ). Other studies have presented evidence supporting Porifera as the sister to Parahoxozoa and Ctenophora as the sister group to the rest of animals (e.g.   ), finding that nervous systems either evolved independently in ctenophores and parahoxozoans, or were secondarily lost in poriferans. If ctenophores are taken to have diverged first, Eumetazoa is sometimes used as a synonym for ParaHoxozoa.

Phylogeny
The tree below, which is congruent with the vast majority of these phylogenomic studies, conveys this uncertainty with a polytomy.

ParaHoxozoa or Parahoxozoa
Though "ParaHox" genes are usually referred to in CamelCase and the original paper that named the clade used "ParaHoxozoa", the single initial capital format "Parahoxozoa" has also come to be used in the literature, as CamelCase is not standard in zoological nomenclature.

Characteristics
Parahoxozoa was defined by the presence of several gene (sub)classes (HNF, CUT, PROS, ZF, CERS, K50, S50-PRD), as well as Hox/ParaHox-ANTP from which the name of this clade originated. It was later proposed and contested that a gene of the same class (ANTP) as the Hox/ParaHox, the NK gene and the Cdx Parahox gene, is also present in Porifera, the sponges. Regardless of whether a ParaHox gene is ever definitively identified, Parahoxozoa, as originally defined, is monophyletic and therefore continues to be used as such.

Planula-acoel, triploblasty, and bilaterian similarities
The original Bilateria are hypothesized to be a bottom dwelling worm with a single body opening. A through-gut may already have developed with the Ctenophora however. The through-gut may have developed from the corners of a single opening with lips fusing. E.g. Acoela resemble the planula larvae of some Cnidaria, which exhibit some bilaterian symmetry. They are vermiform, just as the cnidarian Buddenbrockia is. Placozoans have been noted to resemble planula. Usually, "Planulozoa" refers to a Cnidaria–Bilateria clade to the exclusion of Placozoa, but not necessarily. In the other case, when including all three lineages, it appears synonymous with Parahoxozoa. Triploblasty may have developed before the Cnidaria–Bilateria radiation too.

Taxonomy
The Parahoxozoa has 3 different types of phyla that includes placozoans, cnidarians, and bilaterians.

Placozoans
Placozoans (e.g. Polyplacotoma mediterranea, Trichoplax adhaerens, and Cladtertia collaboinventa) are a phylum of very small animals.

Cnidarians
Cnidarians (e.g. jellyfish, corals, and sea anemones) have stinging cells called cnidocytes.

Bilaterians
Bilaterians (e.g. arthropods, molluscs, and vertebrates) have mirror symmetry for at least part of their embryonic development.