Pee Dee (disambiguation)

Pee Dee is a region of South Carolina.

Pee Dee or Peedee may also refer to:
 * Pedee people, also spelled Pee Dee and Peedee, a Native American people, now concentrated in South Carolina
 * Pee Dee, Anson County, North Carolina, United States, a populated place
 * Pee Dee, Montgomery County, North Carolina, an unincorporated community
 * Pee Dee River, in North and South Carolina
 * Peedee Formation, a geologic formation in North and South Carolina
 * Nickname for the Cleveland Plain Dealer, the major daily newspaper of Cleveland, Ohio, United States
 * PeeDee the Pirate, mascot of the East Carolina Pirates
 * Peedee Fryman, a fictional character on Steven Universe