Phi Sigma Chi

Phi Sigma Chi (ΦΣΧ) may refer to:


 * Phi Sigma Chi (sorority), a nearly 100-year old local sorority formed in 1924 at Grove City College in Grove City, PA
 * Phi Sigma Chi (fraternity), a 13-chapter multicultural fraternity founded on 1996-11-16 at the New York City College of Technology, (CUNY)
 * Phi Sigma Chi (Defiance), a local fraternity formed in 1967 at Defiance College in Defiance, OH, which became the Ohio Omicron chapter of Sigma Phi Epsilon (ΣΦΕ) on 1970-04-04
 * Phi Sigma Chi (Trine), a local fraternity formed in 1927 at Trine University in Angola, IN, which had several fraternal affiliations before becoming the Indiana Theta chapter of Sigma Phi Epsilon (ΣΦΕ) on 1968-05-04
 * Phi Sigma Chi (secondary), a dormant high school fraternity founded on 1900-11-28 in Zanesville, OH, estimated to have chartered 117 chapters