Piccolo (surname)

Piccolo is an Italian surname. Notable people with the surname include:
 * Alessandro Piccolo (agricultural scientist) (born 1951), Italian chemist and agricultural scientist
 * Alessandro Piccolo (racing driver) (born 1980), Italian racing driver
 * Antonio Piccolo (born 1988), Italian footballer
 * Antonio Piccolo (footballer, born 1990), Italian footballer
 * Brian Piccolo (1943–1970), American National Football League player
 * Donato Piccolo (born 1976), Italian artist
 * Felice Piccolo (born 1983), Italian footballer
 * Frank Piccolo (1921-1981), American mobster
 * Francesco Piccolo (born 1964), Italian writer and screenwriter
 * Francisco María Piccolo (1654–1729), Sicilian Jesuit missionary in Mexico
 * María Jimena Piccolo (born 1985), Argentine actress
 * Michele Piccolo (born 1985), Italian footballer
 * Ottavia Piccolo (born 1949), Italian theatre and film actress
 * Renato Piccolo (born 1962), Italian former cyclist
 * Rina Piccolo, Canadian cartoonist
 * Rino Piccolo, international film producer, and film commissioner
 * Sol Piccolo (born 1996), Argentine female volleyball player
 * Tony Piccolo (born 1960), Australian politician