Polynucleotide 3'-phosphatase

The enzyme polynucleotide 3′-phosphatase (EC 3.1.3.32) catalyzes the reaction


 * a 3′-phosphopolynucleotide + H2O $$\rightleftharpoons$$ a polynucleotide + phosphate

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name is polynucleotide 3'-phosphohydrolase. Other names in common use include 2′(3′)-polynucleotidase, DNA 3′-phosphatase, deoxyribonucleate 3′-phosphatase, and 5′-polynucleotidekinase 3′-phosphatase.

Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes and.