Polyphemus (disambiguation)

Polyphemus is a Cyclops in Greek mythology. The name "Polyphemus" may also refer to:
 * Polyphemus (Argonaut), another figure from Greek mythology
 * Antheraea polyphemus, or Polyphemus moth, a giant silk moth of North America
 * Polyphemus (crustacean), a genus of cladocerans
 * Limulus polyphemus, the Atlantic horseshoe crab
 * Mecynorhina polyphemus, a species of beetle
 * Polyphemus (book), a collection of short stories by Michael Shea
 * Polyphemus (Reni), a 1639–1640 painting by Guido Reni
 * Polyphemus (sculpture), an 1888 bronze by Auguste Rodin
 * Polifemo, an Italian opera by Nicola Porpora
 * The name of the gas giant in the Avatar series, which Pandora orbits.