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Mystras (also Mistra, Mystra and Mistras Greek: Μυστράς, Μυζηθράς Mizithras or Myzithras in the chronicle of Morea) was a fortified town in Morea (the Peloponnesus), on Mt. Taygetos, near ancient Sparta. It lies approximately eight kilometres west of the modern town of Sparti.

In 1249, Mystras became the seat of the Latin Principality of Achaea, established in 1205 after the conquest of Constantinople during the Fourth Crusade, and Prince William II Villehardouin, a grand-nephew of the Fourth Crusade historian Geoffrey of Villehardouin, built a palace there.

In 1261, the Latins ceded Mystras and other forts in the southeastern Peloponnese as ransom for William II, who had been captured in Pelagonia, and Michael VIII Palaeologus made the city the seat of the new Despotate of Morea. It remained the capital of the despotate, ruled by relatives of the Byzantine emperor, although the Venetians still controlled the coast and the islands. Mystras and the rest of Morea became relatively prosperous after 1261, compared to the rest of the empire. Under the despot Theodore it became the second most important city in the empire after Constantinople, and William II's palace became the second residence of the emperors.

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