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Marcus Ward Lyon, Jr. was an American mammalogist, bacteriologist, and pathologist. He was born into a military family at Rock Island Arsenal, and demonstrated an early interest in zoology by collecting local wildlife around his father's army posts. He graduated from Brown University in 1897, and continued his studies at George Washington University while working part-time at the United States National Museum (USNM). He received his Ph.D. from George Washington University in 1913. In 1919, he and his wife, Martha, moved to South Bend, Indiana to join a newly opened clinic. Prior to moving, Lyon had published many papers on mammalogy, both during and after his tenure at the USNM. In these papers, he had formally described six species, three genera, and one family. Once in South Bend, he began to publish medical studies, too, but continued his work in mammalogy, with a particular focus on the local fauna of Indiana. He published more than 160 papers during his career.

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