Primera División de México Apertura 2006

Primera División de México (Mexico First Division) Apertura 2006 was the 2006 edition of La Primera División del Futbol Méxicano, crowning Mexico's autumn football champion. The season ran from August 5 to December 10, 2006. Querétaro was promoted to the Primera División de México thus, Dorados was relegated to the Primera División A. Guadalajara won the championship for a record 11th time, qualifying for the CONCACAF Champions' Cup 2007.

Top goalscorers
Players sorted first by goals scored, then by last name. Only regular season goals listed.

Source: MedioTiempo

Repechaje
Toluca won 2–1 on aggregate.

Guadalajara won 6–1 on aggregate.

Quarterfinals
Toluca won 2–1 on aggregate.

Pachuca won 2–1 on aggregate.

América won 6–4 on aggregate.

Guadalajara won 4–2 on aggregate.

Semifinals
Toluca won 2–1 on aggregate.

Guadalajara won 2–0 on aggregate.

Finals
Guadalajara won 3–2 on aggregate.