Progressive cardiac conduction defect

Progressive cardiac conduction defect (PCCD) is a hereditary cardiac condition marked by a progressive delay in impulse conduction via the His-Purkinje system, resulting in right or left bundle branch block (RBBB or LBBB), syncope, and occasionally sudden cardiac death.

Diagnosis
When progressive conduction abnormalities in people under 50 with structurally normal hearts are present but skeletal myopathies are absent, progressive cardiac conduction defect is primarily diagnosed, particularly if there is a family history of PCCD.

Treatment
At the moment, implanting an implantable pacemaker is the only proven treatment for PCCD, regardless of the underlying cause.