ProofPilot

ProofPilot is an American Internet company with offices in New York City. Its namesake product is a digital protocol automation platform that aims to eliminate guesswork and protocol deviations in clinical settings. Chris Venezia joined as the Chief Executive Officer in 2022.

History
ProofPilot grew out of the consulting firm Cyclogram in 2013. Matthew Amsden started Cyclogram in 2005.

Early versions of the platform supported studies in the United States, Brazil and Peru. ProofPilot participated in the BluePrint Health Incubator program in the winter of 2014.

Amsden has talked about the challenges of creating a digital health startup and the cultural disconnect between buyers and venture-capital-backed startups. He says that adhering to the typical venture-backed startup "rulebook" almost killed ProofPilot. The company relaunched the product in late 2017 after not taking on customers for over two years.

Model
The ProofPilot platform is split in three parts. The first allows users the ability to design research studies. The design process (and resulting participant experience) is based on a concept called micro-interactions. Non-experienced study designers can use study templates and fill in the blanks to create a study. The second is the participant experience. After study designers launch the study, it goes through an automatic external regulatory review by Veritas IRB in Montreal, Quebec, Canada. Then, participants begin to engage in the study via mobile phones and desktop computers. ProofPilot has publicly stated it has deprioritized development of a native iOS and Android application because Progressive web apps provide a better user experience. The system also provides reporting of findings.

Regulatory and ethics review
In September 2016, ProofPilot formed a partnership with Veritas IRB in Montreal, Quebec, Canada. Given that many of its customers are not academic institutions and don't have an in-house review process, all studies launched on ProofPilot will be reviewed by Veritas before going live.