Propargylamine

Propargylamine is an organic compound with the formula HC≡CCH2NH2. It is a colorless, odorless liquid that is used as a precursor to other compounds. Propargyl amines are produced by reactions of amines with propargyl halides.

The behavior of propargyl amine is illustrated by its acylation benzoyl chloride to the amide. A Sonogashira coupling of the terminal alkyne end with another equivalent of benzoylchloride gives the dicarbonyl, a precursor to an oxazole.
 * [[Image:OxazoleFrompropargylamide.png|300px|oxazoline from propargyl amides Merkul 2006]]

Drugs
Propargylamine is used in the synthesis of:
 * 1) Etintidine [69539-53-3]
 * 2) 2-PAT
 * 3) HDAC1/MAO-B-IN-1 [2759855-37-1]