Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing)

Pyridoxal 5′-phosphate synthase (glutamine hydrolysing) (EC 4.3.3.6, PdxST) is an enzyme with systematic name  D -ribose 5-phosphate, D -glyceraldehyde 3-phosphate pyridoxal 5′-phosphate-lyase. This enzyme catalyses the following chemical reaction


 * D -ribose 5-phosphate + D -glyceraldehyde 3-phosphate + L -glutamine $$\rightleftharpoons$$ pyridoxal 5′-phosphate + L -glutamate + 3 H2O + phosphate (overall reaction)
 * (1a) L -glutamine + H2O $$\rightleftharpoons$$ L -glutamate + NH3
 * (1b) D -ribose 5-phosphate + D -glyceraldehyde 3-phosphate + NH3 $$\rightleftharpoons$$ pyridoxal 5′-phosphate + 4 H2O + phosphate

The enzyme can also use ribulose 5-phosphate and dihydroxyacetone phosphate.