Pyrimidine analogue

Pyrimidine analogues are antimetabolites which mimic the structure of metabolic pyrimidines.

Examples

 * Nucleobase analogues
 * Fluorouracil (5FU), which inhibits thymidylate synthase
 * Floxuridine (FUDR)
 * 6-azauracil (6-AU)
 * Nucleoside analogues
 * Cytarabine (Cytosine arabinoside)
 * Gemcitabine
 * Nucleotide analogues

Medical uses
Pyrimidine antimetabolites are commonly used to treat cancer by interfering with DNA replication.