Quinolinate synthase

Quinolinate synthase (, NadA, QS, quinolinate synthetase) is an enzyme with systematic name glycerone phosphate:iminosuccinate alkyltransferase (cyclizing). This enzyme catalyses the following chemical reaction


 * glycerone phosphate + iminosuccinate $$\rightleftharpoons$$ pyridine-2,3-dicarboxylate + 2 H2O + phosphate

This iron-sulfur protein that requires a [4Fe-4S] cluster for activity.