RAB5A

Ras-related protein Rab-5A is a protein that in humans is encoded by the RAB5A gene.

Function
RAB5A localizes to early endosomes where it is involved in the recruitment of RAB7A and the maturation of these compartments to early endosomes. It drives the maturation of endosomes by transporting vacuolar (H+)-ATPases (V-ATPases) from trans-Golgi network to endocytic vesicles.

Interactions
RAB5A has been shown to interact with:


 * CHML,
 * RABEP1,
 * SDCBP, and
 * ZFYVE20