RSSB

RSSB may refer to:


 * Rail Safety and Standards Board, a British non-for-profit independent company
 * Rajasthan Staff Selection Board, selects people for the civil service in Rajasthan, India
 * Radha Soami Satsang Beas, a spiritual organization based in Punjab, India
 * Royal Statistical Society of Belgium
 * RssB, a specialized anti-sigma factor in gene expression