Racquetball at the 2022 World Games – Women's singles

The women's singles event in racquetball at the 2022 World Games took place from 10 to 13 July 2022 at the University of Alabama Birmingham in Birmingham, United States.

Mexican Paola Longoria won the competition, defeating Guatemalan Gabriela Martinez in the final.

Competition format
A total of 16 athletes entered the competition. They competed in knock-out system.