Ribonucleotide reductase inhibitor

Ribonucleotide reductase inhibitors are a family of anti-cancer drugs that interfere with the growth of tumor cells by blocking the formation of deoxyribonucleotides (building blocks of DNA).

Examples include: name="PharmRev">
 * motexafin gadolinium.
 * hydroxyurea
 * fludarabine, cladribine, gemcitabine, tezacitabine, and triapine
 * gallium maltolate, gallium nitrate<ref
 * Tezacitabine, Tezacitabine A chemotherapy candidate nucleotide analogue that failed in clinical trials due to on-target toxicity (febrile neutropenia).