Robert Clayton

Robert Clayton may refer to:
 * Robert Clayton (bishop) (1695–1758), Irish Protestant bishop
 * Robert Clayton (City of London MP) (1629–1707), Lord Mayor of London, MP for the City of London and for Bletchingley
 * Robert Clayton (cricketer) (1844–1901), Welsh cricketer
 * Sir Robert James Clayton (1915–1998), British electronics engineer and executive
 * Robert N. Clayton (1930–2017), Canadian-American National Medal of Science laureate
 * Rob Clayton, American painter, one of the Clayton Brothers
 * Bob Clayton (1922–1979), American game show host
 * Bob Clayton (footballer), Australian rules footballer
 * Clayton baronets:
 * Sir Robert Clayton, 2nd Baronet, of Adlington (1746–1839)
 * Sir Robert Clayton, 3rd Baronet, of Marden (c. 1740–1799), MP for several seats
 * Sir Robert Alan Clayton-East-Clayton, 9th Baronet Clayton, of Marden (1908–1932)
 * Sir Robert Alan Clayton East-Clayton, 5th Baronet of Hall Place, Maidenhead (1908–1932)
 * Sir Robert Clayton, 13th Baronet of Marden (1975-)