Ruffo

Ruffo is a surname. Notable people with the surname include:

Noble house of Ruffo di Calabria

 * Fabrizio Ruffo (1744–1827), Italian cardinal
 * Fulco Ruffo di Calabria (1884–1946), Italian World War I flying ace
 * Giordano Ruffo (1200-1256), Italian nobleman and early writer on equestrian medicine
 * Paola Ruffo di Calabria (born 1937), queen consort of Belgium
 * Tommaso Ruffo (1663–1753), Italian cardinal
 * Polissena Ruffo (1400–1420), princess of Calabria

Others

 * Albert J. Ruffo (1908–2003), American politician
 * Andrée Ruffo, Canadian judge
 * Antonio Ruffo (1610s–1678), Sicilian politician, nobleman, patron, and collector
 * Armand Garnet Ruffo (born 1955), Canadian scholar, filmmaker, writer and poet
 * Bruno Ruffo (1920–2007), Italian motorcycle road racer
 * Dennis Ruffo, Canadian music promoter
 * Ernesto Ruffo Appel (born 1952), American-born governor of Baja California
 * John Ruffo (born 1954), American business executive
 * Johnny Ruffo (1988–2023), Australian singer, songwriter, dancer, actor and television presenter
 * Leonora Ruffo (1935–2007), Italian film actress
 * Marco Ruffo, Italian architect
 * Pietro Ruffo (born 1978), Italian artist
 * Titta Ruffo (1877–1953), Italian baritone
 * Victoria Ruffo (born 1962), Mexican actress
 * Vincenzo Ruffo (c. 1508–1587), Italian composer of the Renaissance