Rufina (disambiguation)

Rufina is a commune in Tuscany.

Rufina may also refer to:
 * Rufina (name), a female first name and surname
 * Rufina, Guayanilla, Puerto Rico, a barrio in Puerto Rico
 * Rufina Patis, Philippine brand of fish sauce made by fermenting salted fish for several months
 * Efferia rufina, species of insect