S-Glutathionylation

S-Glutathionylation is the posttranslational modification of protein cysteine residues by the addition of glutathione, the most abundant and important low-molecular-mass thiol within most cell types.

Protein S-glutathionylation is involved in
 * oxidative stress
 * nitrosative stress
 * preventing irreversible oxidation of protein thiols
 * control of cell-signalling pathways by modulating protein function