S. Harris

S. Harris may refer to:


 * Sampson Willis Harris (1809-1857), American politician
 * Sidney Harris (born 1933), American cartoonist
 * Sadie Harris, fictional character from the television show Grey's Anatomy
 * S. Harris, co-writer with Juan Tabo of the short story "If You Were an Award, My Love"
 * Shyamala Gopalan, married as Shayamala Gopalan Harris