S101

S101 may refer to:


 * Asus Eee PC S101, a netbook computer from Asus
 * Dome S101, a sports car prototype for endurance racing
 * Highway S101, proposed northern extension of New Jersey Route 101, never built
 * HMS Dreadnought (S101), the United Kingdom's first nuclear-powered submarine
 * New Jersey State Highway S101, a controlled-access toll road running north–south in eastern New Jersey
 * SAS Manthatisi (S101), a Heroine-class submarine in service with the South African Navy
 * Soviet submarine S-101, Stalinets-class submarine of the Soviet Navy