S120

S120 may refer to :
 * HMS Ambush (S120), a 2007-2008 proposed Astute-class nuclear Fleet submarine of the Royal Navy
 * S Papanikolis (S 120), a Type 214 submarine
 * RENFE Class 120 (RENFE Serie 120 or S-120) high speed train
 * Canon PowerShot S120 digital camera