S48

S48 may refer to:

Aviation

 * Blériot-SPAD S.48, a French biplane airliner
 * Country Squire Airpark in Clackamas County, Oregon, United States
 * SABCA S-48, a Belgian aircraft
 * Sikorsky S-48, an American helicopter

Other uses

 * S48 (New York City bus) serving Staten Island
 * County Route S48 (Bergen County, New Jersey)
 * HMS Conqueror (S48), a submarine of the Royal Navy
 * S48: Keep wet with ... (appropriate material to be specified by the manufacturer), a safety phrase
 * USS S-48 (SS-159), a submarine of the United States Navy