S74

S74 may refer to:
 * S74 (Long Island bus)
 * S74 (New York City bus) serving Staten Island
 * Birrana S74, an Australian speedcar
 * Expressway S74 (Poland)
 * Fiat S74, a racing car
 * HMCS Okanagan (S74), a submarine of the Canadian Forces
 * Savoia-Marchetti S.74, an Italian airliner
 * Sikorsky S-74, an American helicopter design
 * SPANISH SUBMARINE Tramontana
 * S74, a postcode district for Barnsley, England