SACS

SACS may refer to:
 * SACS, a finite element analysis software by Bentley Systems
 * SACS (gene), a human gene that encodes the protein Sacsin
 * The South Atlantic Cable System, a transoceanic submarine communications cable
 * Saint Alphonsus Catholic School, a Catholic School found at Lapu-Lapu City, Cebu, Philippines
 * St Andrew's Cathedral School, an Anglican school in Sydney, Australia
 * The South African College Schools, a school in Cape Town, South Africa
 * The Southern Association of Colleges and Schools, an educational accreditation body in the southern United States
 * Success Academy Charter Schools
 * Southwest Allen County Schools, a school district in Indiana
 * Suzuki Advanced Cooling System, used in some Suzuki motorcycle engines