SC-5

SC-5, SC5, SC 5 or variants, may refer to:


 * SC05, an FIPS 10-4 region code
 * SC-05, a subdivision code for Anse Royale, Seychelles, see ISO 3166-2:SC
 * South Carolina's 5th congressional district
 * South Carolina Highway 5
 * USS Cuttlefish (SC-5)
 * SpaceX Crew-5

Video games

 * Soulcalibur V
 * Space Channel 5