SC3

SC3 may refer to:


 * South Carolina's 3rd congressional district
 * South Carolina Highway 3, a state highway in South Carolina
 * Santa Clause 3: The Escape Clause, a 2006 American film that is third in the Santa Clause movie series
 * SC3, a spin-off pop-group, made of 3 original members of S Club 7
 * Secret Chiefs 3, an avant-garde/experimental instrumental rock music group
 * USS SC-3, a United States Navy submarine chaser commissioned in 1918 and sold in 1920
 * SC3, a candidate phylum of bacteria from arid soil
 * SC03, a FIPS 10-4 region code, see List of FIPS region codes (S–U)
 * SC-03, a subdivision code for the Seychelles, see ISO 3166-2:SC

Video games

 * Soul Calibur III, a PlayStation 2 fighting game produced by Namco
 * Star Control 3, a video game developed by Legend Entertainment
 * SimCity 3000, a city-building simulation personal computer game and the third major installment in the SimCity series
 * Tom Clancy's Splinter Cell: Chaos Theory, a third-person stealth-based video game also known as Splinter Cell 3