SFN

SFN may refer to:


 * Short filename, the 8.3 filename limitation of the DOS computer operating system
 * SFN Group, Inc., a North American temporary work agency
 * Single-frequency network, a broadcast network where several transmitters simultaneously send the same signal over the same frequency channel
 * Small Fiber Neuropathy
 * Society for Neuroscience, a professional society headquartered in Washington, D.C.
 * Subcutaneous fat necrosis of the newborn, a medical condition occurring in newborns
 * Protein stratifin